A novel biomimetic membrane that simulates and buccal mucosa

PermeaPad GIT

Application with our Permetro system:

Permetro system application.pdf

We suggest performing in-vitro dissolution & permeation assays before BA/BE studies. Generate a dynamic absorption profile to mimic in-vivo drug absorption.

  • For in-vitro permeation study
  • Ready to use membrane
  • To test drug permeation completely animal cruelty free
Membrane components  Cellulose membrane + Lecithin (S-100) + Fliter paper
Disk Diameter 1.    25,0 + 0,2 mm

2.    35,0 + 0,2 mm
Storage Do not expose the product to sun and UV radiation and store at 25 °C.
Operation temperature e.g. 25 °C; 37 °C
Measuring range pH 1-10 ;

pH gradient can be maintained for hours
Drug concentration e.g. 5 mM
Sampling intervals Freely selectable
Test duration Up to 24 h
Analysis method  e.g.  HPLC, LC-MS/MS, etc.
Data Permeation, Flux, apparent permeation coefficient Papp drug recovery
Tested drug substances Acyclovir, Atenolol, Calcein, Caffeine, Donepezil HCl, Hydrocortisone, Ibuprofen, Nadolol, Metoprolol, Paracetamol, Theobromine, Theophylline, Verapamil HCl
Warranty Expiry date on labe

For enquires from Europe, please contact Biomedica.

For enquires from India, please contact Electrolab.