Application with our Permetro system:
Permetro system application.pdf
We suggest performing in-vitro dissolution & permeation assays before BA/BE studies. Generate a dynamic absorption profile to mimic in-vivo drug absorption.
| Membrane components | Cellulose membrane + Lecithin (S-100) + Fliter paper |
| Disk Diameter |
1. 25,0 + 0,2 mm 2. 35,0 + 0,2 mm |
| Storage | Do not expose the product to sun and UV radiation and store at 25 °C. |
| Operation temperature | e.g. 25 °C; 37 °C |
| Measuring range |
pH 1-10 ; pH gradient can be maintained for hours |
| Drug concentration | e.g. 5 mM |
| Sampling intervals | Freely selectable |
| Test duration | Up to 24 h |
| Analysis method | e.g. HPLC, LC-MS/MS, etc. |
| Data | Permeation, Flux, apparent permeation coefficient Papp drug recovery |
| Tested drug substances | Acyclovir, Atenolol, Calcein, Caffeine, Donepezil HCl, Hydrocortisone, Ibuprofen, Nadolol, Metoprolol, Paracetamol, Theobromine, Theophylline, Verapamil HCl |
| Warranty | Expiry date on labe |
For enquires from Europe, please contact Biomedica.
For enquires from India, please contact Electrolab.
