FTC-800 Automated Flow-through Diffusion Cell System

FTC-800

Brochure (please click to download): Brochure_FTC-800 System

Flow-through Diffusion is designed to simulate the process of drug permeation through a biological or synthetic barrier. These in vitro permeation tests (IVPT) can be used to evaluate API permeation performance in a variety of topical dosage forms including semi-solids, ointments, gels, creams, oils, liquids, transdermal patches and more.

The FTC-800 Automated Flow-through Diffusion Cell system is a USP <1724> compliant tool that can accommodate up to eight dry heat flow-through cells, offering scalability and flexibility to meet diverse research needs. The ultra-smooth, precision syringe pumping system assures a steady, pulseless flow which reduces variabilities that other pumping methods may introduce. The FTC-800 consists of a tiltable flow-through cell holder, a dual eight-channel syringe-based autosampler-controller, and sample collector. Our patented high-precision PEEK flow-through cells are designed to ensure the skin is smooth and taut throughout the test run.

Features
  • Complies with USP <1724>
  • Dry heat flow-through cell technology
  • Precision-flow syringe pump system
  • Programmable flow rates from 0.1 – 4.0 mL
  • Individual cell temperature monitoring
  • Bubble-free tilt manifold prevents bubble formation
  • A variety of PEEK flow-through cell options
FTC-800 Flow-Through System Diagram

The offset precision dual-syringe pump pulls media from the external reservoir, pushes it through heated lines into the preheat station, then into the heated flow-through cell, and finally out to waste and/or into collection tubes, all with a smooth, uniform, pulseless flow for the duration of the test run. Receptor media temperature is closely monitored at the inlet of each flow-through cell.

Citations